This was the world of Earth A.D. (After Disaster), and the world Kamandi, the Last Boy On Earth, set out to explore.
Sadly, he didn't have a map with which to explore it!
Here, he encountered Great Caesar and his tiger-men cavalry, who were battling the leopard men. Kamandi was captured, and taken to the human slave pits (the mutated men thinking Kamandi just a dumb animal, which all humans had fallen to). There, he met the talking bulldog scientist Doctor Canus, who took an interest in the boy, and introduced him to Ben Boxer, a radioactive android who looked like a normal human...
The issue had a new story as well, entitled "Me!", with with Kamandi, Dr. Canus, Ben Boxer and Prince Tuftan (the son of Great Caesar) fighting gorilla commandos and meeting a new alien, which would come to figure in the future of Kamandi!
The issue also contained a lengthy article on the penciling talent of Jack Kirby, written by Steve Sherman.
Jack would soon leave the title after this story, but with this and other works, DC writers would start to flesh out the world after the Great Disaster (more on that here!), and though they took it in some unexpected directions, Kirby had laid out the map!Steel the Indestructible Man #6, Secret Society of Super-Villains #16 and #17 and more!