....yet, the effects of going into space and landing on the moon have been felt by the heroes of Earth...
...just take a look at Moon Man and Lady Lunar!
There must have been some green kryptonite in that meteor as well, as the green glow Moon Man put off weakened Superman...and it took the help of Batman and Robin to help Brice Rogers see the light of day and be rid of his evil alter ego of the Moon Man!
As Lady Lunar, Stacy's personality split, and she had the same gravity and hypnotic powers the Moon Man did. Lady Lunar kidnapped Dr. Jenet Klyburn of S.T.A.R. Labs, used her knowledge to help make a bomb (and as bait to capture Batman), and planned to blow up Metropolis under the cover of night. If not for Superman making solar reflectors to blanket Metropolis with sunlight, Lady Lunar may have succeeded!
One never knows what dooms could be unleashed on mankind if Moon Man or Lady Lunar returned...