"That's one small step for [a] man, and one giant leap for mankind".
....wherein three of the Fantastic Four were behind the scenes, fighting Kree Sentry #9168, while Sue was still back on Earth, recovering from the birth of her son, Franklin Richards! The "a" was something Neil Armstrong said he had said, but static interfered with it in the transmission to Earth).
Quite a moving scene..
....but, the Fantastic Four had been to the moon before!
Feels Like The First Time
Love Is A Battlefield
the X-Men battled the Imperial Guard for the life of what they thought was Jean Grey (really, the Phoenix) all in X-Men #137 (September, 1980 by Chris Claremont and John Byrne). Wolverine even has a brief encounter with the Watcher in his citadel (that does not go well for Wolverine).
Moving On Up
...after the Earth had become too polluted for them to live their, even in their hidden city of Attilan (also called the Great Refuge).
(The city of Attilan first appeared in Fantastic Four #47 by Stan Lee and Jack Kirby, February, 1966 and the Inhumans as a whole first appeared in Fantastic Four #45, December, 1965, also by Lee and Kirby), with Attilan moving to the moon in Fantastic Four #240 (March, 1982, by John Byrne).
...and a reawakening of their Kree genes, as the Inhumans were descendants of humans experimented on by the Kree.
These powers were often unpredictable....and changed the recipients in unexpected ways.
Randac's story started in Thor #146 (November, 1967), with more tales of the early Inhumans (pre-Fantastic Four meeting) coming in Thor #147 (in December, 1967, with Sentry #459 being activated by Randac's work as Randac planned to expose all his people to the Terrigan Mist), and the youth of Inhumans leader Black Bolt, getting his time and powers with the mist, in Thor #148 (January, 1968) and Black Bolt, Medusa, Maximus and Triton history until Thor #152 (May, 1968).
Kree-Skrull War in Avengers #95 (January, 1972).
So, with all this, you can see how connected all of Lee and Kirby's creations are, and that the imagination to take us to the moon, also connected to our fantasies of how we see ourselves in the stars and how we are all connected in our dreams!