It's a comic based on the TV show, and plans to have Agent Coulson and his team working in the current comic universe, introducing Melinda May, Leo Fitz and Jemma Simmons into the Marvel Universe (as opposed to the Marvel Cinematic Universe) in a series of stories by Mark Waid (and first issue containing art by Carlos Pacheco and later issues by Chris Sprouse and Alan Davis). CBR interviewed Mark Waid, and he discussed his plans for Phil Coulson and crew here.
But, what of other, comic book agents of S.H.I.E.L.D.?
Super-Agents of S.H.I.E.L.D.
Like S.H.I.E.L.D. (whose history is touched on here along with their villainous counterpart, Hydra), these characters have connections all over the Marvel Universe (the Falcon, Cap's frequent partner, to get more coverage under the Avengers).
The Vamp and the Blue Streak
From there, using his powers of flight, strength and energy manipulation granted by the bands, Quasar kept going until Quasar #60 (July, 1994), with Mark Gruenwald writing almost all the issues, and having Quasar meet with or fight a vast array of the Marvel Universe...